| |
| Institution: |
University of Maryland, Baltimore |
| Docket: |
RR-2006-055 |
| Title: |
Multiplexed Laboratory Animal Monitoring System (MLAMS) |
| Summary: |
The present invention relates to a novel multiplexed laboratory animal monitoring system (MLAMS). This computer based monitoring system allows 24-hour, 7 day a week automated activity monitoring of laboratory animals
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| Applications: |
Pharmaceutical drug testing in laboratory animals.
Health monitoring of laboratory animals.
Inventory monitoring of laboratory animals.
Measurement of certain physiological and behavioral parameters, including measurement of activity levels, diurnal patterns, and quantitation of toxic endpoints.
|
| Advantages: |
Laboratory animals can be monitored relatively inexpensively
compared to other systems.
Significantly reduce operator input.
Minimize the number of animals needed per study.
Allow for more rapid identification of disease, toxicity or drug effects.
Provide more accurate experimental data by reducing or eliminating mistakes in laboratory animal diagnosis.
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| State of Development: |
Proof of concept being validated in a hamster model of scrapie. |
| R and D Required: |
Further testing with scrapie model and other species/diseases models required |
| Licensing Potential: |
UM seeks to develop and commercialize via an exclusive or
non-exclusive license agreement and/or sponsored research with a company active in the area.
|
| Patent Status: |
Patent pending |
| Related Publications: |
Boisvert, M. J. & Sherry, D. F. (2000). A system for the automated
recording of feeding behavior and body weight. Physiol Behav 71,
147-151.
Quinn, L. P., Stean, T. O., Trail, B., Duxon, M. S., Stratton, S. C.,
Billinton, A. & Upton, N. (2003). LABORAS: Initial pharmacological
validation of a system allowing continuous monitoring of laboratory
rodent behaviour. J Neurosci Methods 130, 83-92.
Van de Weerd, H. A., Bulthuis, R. J., Bergman, A. F., Schlingmann, F.,
Tolboom, J., Van Loo, P. L., Remie, R., Baumans, V. & Van Zutphen, L.
F. (2001). Validation of a new system for the automatic registration
of behaviour in mice and rats. Behav Processes 53, 11-20.
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| Technology Inventors: |
G. Peter Sawiris
Robert G. Rohwer
|
| Contact Info: |
Technology Licensing Officer
cvip@umaryland.edu
620 West Lexington St.
Baltimore, MD, 21201
410-706-1187 |
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