| |
| Institution: |
University of Maryland, Baltimore |
| Docket: |
LZ-2004-064 |
| Title: |
A Novel Surface Marker for the Enrichment and Expansion of the Stromal Stem Cell Population |
| Summary: |
A novel method to obtain and culture a pure population of adult human or mouse bone marrow stromal stem cells (BMSSCs) in large numbers. |
| Applications: |
Hematopoietic diseases
Birth defects
Trauma
Disease processes leading to dysfunctional bone and/or low bone mass
Orofacial and plastic surgery
Bone marrow ex vivo
Vehicles for gene therapy |
| Advantages: |
Superior to currently available methods using known surface markers for BMSSCs. |
| State of Development: |
The novel surface marker has been characterized and used to enrich BMSSCs. |
| R and D Required: |
Demonstration of the differentiation capability of purified stem cells into, for example, osteoblasts, chondrocytes, and adipocytes.
Successful isolation of stromal stem cells from adipocyte tissue.
Proof of concept for clinical application. |
| Licensing Potential: |
UMB seeks to develop and commercialize via an exclusive or non-exclusive license agreement and/or sponsored research with a company active in the area. |
| Patent Status: |
PCT/US05/32220 filed on September 6, 2005. |
| Related Publications: |
Manuscript in preparation. |
| Files: |
|
| Technology Inventors: |
Lijun Zhang
Shi Songtao
Yasuo Miura
|
| Contact Info: |
Technology Licensing Officer
cvip@umaryland.edu
620 West Lexington St.
Baltimore, MD, 21201
410-706-1187 |
